Comprehensive Guide to Imfinzi (Durvalumab): Pricing, Uses, and More
Imfinzi (durvalumab) is an innovative immunotherapy drug that has transformed the treatment landscape for various types of cancer. Developed by AstraZeneca, it belongs to the class of anti-PD-1 and PD-L1 monoclonal antibodies, functioning as an immune checkpoint inhibitor. This guide aims to provide an in-depth look at Imfinzi, including its applications, pricing, and patient assistance options.
Comparison of Imfinzi Applications
| Cancer Type | Indication | Administration | Typical Dosage |
|---|---|---|---|
| Non-Small Cell Lung Cancer | Advanced or metastatic | Intravenous infusion | 10 mg/kg every 2 weeks |
| Small Cell Lung Cancer | Extensive-stage | Intravenous infusion | 10 mg/kg every 2 weeks |
| Biliary Tract Tumor | Locally advanced or metastatic | Intravenous infusion | 10 mg/kg every 2 weeks |
| Bladder Cancer | Muscle-invasive or metastatic | Intravenous infusion | 10 mg/kg every 2 weeks |
| Endometrial Cancer | Advanced or recurrent | Intravenous infusion | 10 mg/kg every 2 weeks |
Overview of Imfinzi
Imfinzi has gained FDA approval for treating various cancers, including non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), bladder cancer, biliary tract tumors, and endometrial cancer. It is typically administered as an intravenous infusion in a clinical or hospital setting. The drug works by enhancing the immune response against cancer cells, potentially leading to improved overall survival rates.
Mechanism of Action
Imfinzi functions by blocking the PD-L1 protein, which cancer cells often exploit to evade the immune system. By inhibiting this pathway, Imfinzi allows immune cells to recognize and attack cancer cells more effectively. This mechanism is pivotal in the context of solid tumors, where the immune response can be suppressed.
Side Effects
Patients using Imfinzi may experience side effects, which can range from mild to severe. Common side effects include:
- Fatigue
- Cough
- Nausea
- Loss of appetite
- Diarrhea
- Skin rash
- Shortness of breath
Patients are encouraged to communicate any adverse symptoms to their healthcare providers promptly.
Pricing of Imfinzi
The cost of Imfinzi can vary significantly based on several factors, including pharmacy location, insurance coverage, and patient discounts.
Price Breakdown
- Imfinzi (50 mg/mL): Approximately $1,089 for a 2.4 mL supply.
- Imfinzi (500 mg/10 mL): Pricing may vary; typically higher due to dosage.
Prices are generally quoted for cash-paying customers and do not account for insurance discounts. Patients should also consider using discount cards available at platforms like Drugs.com and GoodRx for potential savings.
Factors Influencing Cost
- Insurance Coverage: The out-of-pocket cost can differ significantly based on insurance plans.
- Pharmacy Location: Prices can vary by geographic location and specific pharmacy.
- Patient Assistance Programs: Programs from Imfinzi and other organizations can help reduce the financial burden.
Financial Assistance Options
For patients struggling with the cost of Imfinzi, various financial assistance options are available:
- Manufacturer Programs: Imfinzi’s official website offers patient assistance programs for eligible individuals.
- Nonprofit Organizations: Organizations such as Medical News Today provide resources to help patients navigate financial challenges related to their treatment.
- Discount Cards: Websites like PharmacyChecker and RxSaver offer discount programs that can help lower medication costs.
Technical Features of Imfinzi
| Feature | Details |
|---|---|
| Generic Name | Durvalumab |
| Drug Class | Anti-PD-1 and PD-L1 monoclonal antibodies |
| Formulation | Intravenous infusion |
| FDA Approval Date | May 1, 2017 |
| Common Side Effects | Fatigue, cough, nausea, diarrhea |
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Conclusion
Imfinzi represents a significant advancement in cancer treatment, specifically for conditions like NSCLC, SCLC, and bladder cancer. Understanding its pricing, applications, and available financial assistance can empower patients to make informed decisions about their treatment options. By leveraging resources like Drugs.com, GoodRx, and Imfinzi, patients can navigate their treatment journey more effectively.
FAQ
What is Imfinzi used for?
Imfinzi is primarily used to treat various types of cancer, including non-small cell lung cancer, small cell lung cancer, bladder cancer, biliary tract tumors, and endometrial cancer.
How is Imfinzi administered?
Imfinzi is administered as an intravenous infusion, typically in a clinical or hospital setting.
What are the common side effects of Imfinzi?
Common side effects include fatigue, cough, nausea, loss of appetite, diarrhea, skin rash, and shortness of breath.
How much does Imfinzi cost?
The cost of Imfinzi can vary, but it is approximately $1,089 for a 2.4 mL supply for cash-paying customers.
Does insurance cover Imfinzi?
Insurance coverage for Imfinzi can vary based on the specific insurance plan. Patients should check with their insurance provider for details.
Are there any financial assistance programs for Imfinzi?
Yes, there are financial assistance programs available through the manufacturer and nonprofit organizations that can help alleviate the cost.
What is the mechanism of action of Imfinzi?
Imfinzi works by blocking the PD-L1 protein on cancer cells, enabling the immune system to recognize and attack these cells more effectively.
How often is Imfinzi administered?
Imfinzi is typically administered every 2, 3, or 4 weeks, depending on the patient’s condition and treatment plan.
Can I use discount cards for Imfinzi?
Yes, patients can use discount cards available through various platforms to potentially lower the cost of Imfinzi.
Where can I find more information about Imfinzi?
For more information, consult resources like Drugs.com, GoodRx, and Imfinzi.